Abstract: In this study the plant by-products and the waste of some food processing or farm land wastes are very rich in the natural antioxidants. There for the aim of this study was to investigate the utilization of these compounds in protection or prevention of some human diseases.
The present study was conducted to studying the effect of the polyphenols compounds extracted from dried (Artichoke leaf, Olives leaf and Red grape seeds) on some liver diseases. The main objective of this study is Comparison between the extraction solvents (water – ethanol) on the total content and the polyphenols fractions of (Artichoke leaf, Olives leaf and Red grape seeds) determine by HPLC. Effect of adding the polyphenols water extract of the above three materials on the cooking quality and sensory evaluation of the (paste) as a function food. Effect of adding these paste to the diet of the adult mail albino rats treated with carbon tetrachloride (CCl4) induced liver damage. It can be observed that , ethanol was the more effective solvent for extraction of poly phenols than water, where the ethanol extract contain phenol fractions higher than the water extract in both artichoke and olive leaves as well as ethanol extract showed high concentrate of the total phenolic compounds identified compared with those of water extract. Where artichoke, olive leaves and red grape seeds recorded 712.95, 235.19 and 463.38 for ethanolic extract compound with 426.5, 127.11 and 51.89 mg/100 g for the water extract, respectively.
Finally, the results obtained from the biochemical analysis of the rats serum and histopathological examination of the liver refer to a marked improvement in the health status of the rats after administration the water extracts of the artichoke, olive leaves and red grape seeds.
However, this study could not determine which of these extracts the better is. we suggest further studies with a focus on the extraction methods, doses used and experimental period

Key words: Waste, By-products, Artichoke leaves, Olive leafs, Red grape seeds, Polyphenols, Liver diseases, CCl4.
Publication year 2014
Organization Name
Country Egypt
Author(s) from ARC
Publication Type Master Thesis