Comparative biological and immunological studies on rift valley fever virus (rvfv)strains isolated during and after the epidemic periods

Abstract: In this study, comparative biological and serological investigations were performed on nine isolates of Rift Valley Fever virus obtained during the epidemic and interepidemic period.
These isolates were: Human / z / 501, Sheep / 253 / Menya, Horse / Strain, Giza, Rodent / 817 / RRF and Rodent /820 / RRF, Sharkia, (isolated during 1977), Rodent / 867 / RRF, Sharkia, 1978, Human / sera / 1919 (Qalubia, 1980), Human / Ocular (Fayoum, 1981) and then Rodent / 1852 / RRF (Giza, 1982).
The results revealed the following:-
a) Human isolates seem to be more related to the classical sheep isolate than to rodents and equine isolate by using neutralization test.
b) The cross CF and HI tests showed that the sheep / 258 / isolate is more related to the human isolate Z/ 501 than the other human isolates and is more remotely related to the equine and rodent isolates.

In conclusion, the success of this trial in the production of potent RVF virus antigens of acceptable titers for ELISA assays eventually leads to the production of these antigens in large quantities. These antigens can be provides to research and diagnostic laboratories involved in RVF research and surveillance programs especially countries bordering endemic areas and present the Vet. Serum and Vaccine Research Institute, Cairo as reliable source for RVF antigens.
Publication year 1987
Availability location معهد بحوث الامصال واللقاحات البيطرية
Availability number
Organization Name
Country Egypt
Author(s) from ARC
External authors (outside ARC)
    اسماعيل محمد رضا كلية الطب البيطرى جامعة القاهرة
    رفقى محمد القرمانى الهيئه العامه لإنتاج الأمصال واللقاحات
Agris Categories Animal diseases
AGROVOC
TERMS
Rift valley fever virus.
Proposed Agrovoc Biological and immunological;
Publication Type PhD Thesis