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Some studies on sheep vaccinated with smithburn Attenuated rift valley fever vaccine
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Abstract: This study was performed on 9 adult sheep divided into 3 groups one group included no pregnant vaccinated sheep, second group was pregnant vaccinated ewes and the third group was no pregnant non-vaccinated kept as control. Some of the vaccinated animal showed a slight elevation of body temperature. Two pregnant ewes delivered normal lambs, while the 3rd ewe was aborted one month after vaccination RVF virus was isolated from different organs of the aborted foetus. No significant changes were found in total protein, serum Glutamic oxaloacetic transaminase (GOT) and serum pyrovic transaminase (GPT) than values as compared with non-vaccinated control animals. However there was significant decrease in albumin value and significant increase in globulin value than in control animal animals. The neutralizing antibodies were still detectable at protective level till 36 month post- vaccination. The immunoglobulin as detected by enzyme linked immunosorbent assay (ELISA) were recorded as optical density reading and the results were correlated with those obtained by serum neutralization test (SNT).
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Publication year |
2001
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Pages |
1141-1149
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Availability location |
معهد بحوث الامصال واللقاحات البيطرية
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Availability number |
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Organization Name |
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City |
القاهرة
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serial title |
المجلة المصرية للبحوث الزراعية
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Author(s) from ARC |
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External authors (outside ARC) |
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Agris Categories |
Animal diseases
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Proposed Agrovoc |
Rift valley fever vaccine;Sheep-Vaccines;
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Publication Type |
Journal
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