Influence of vaccination with different avian influenza vaccines at one or seven days-old on productivity, blood biochemical and immune response of broiler chicks
Abstract: This trial was carried out to investigate the effect of different Avian influenza “A1” vaccines (H.5Nl, H.5N2, combinant A1 H5N2 + Newcastle Disease ''ND” and Egyptian H5N1 and vaccination programs (at 1 or 7 days-old) on broiler productivity, physiology and immunology. 1,350 day-old Hubbard broiler chicks were divided into 9 groups Eight group of chickens (3 replicates per group) were vaccinated with H5N 1. H5N2. AI+ /VD and the Egyptian vaccine H5N1 at 1 or 7 days-old The Egyptian vaccine was prepared from the isolated H5N1 Al virus from the Egyptian infected chickens in 2006. The chicken of group 9 were kept as negative control, All chicks had ad libitum access to water corn-soy-based starter diet from 1 to 21 days-old grower diet from 22 to 3 days-old and finisher diet from 31 to -12 days-old Productive traits were measured weekly and calculated globally from 1 to 42 days-old Five blood samples per replicate were collected at 4. 7. 14. 21. 28. 35 and -12 days-old During the experimental period, results indicated that neither different vaccines nor vaccination programs affect broiler productivity. ND titer (ranged from 3 to 7) and relative spleen (ranged from 125 to 197 mg/100 g BW) or bursa (ranged from 51 to 159 mg/100 g BW) weights. On the hand, this study revealed that. H5N2 and Al + ND vaccines were more protective than H5N1 or the Egyptian Al vaccines as indicated by the geometric mean of Hl titer against AI virus or experimentally broiler chich (5.71 to 8.20 vs. 0 to 4.9 respectively). However no differences were detected among the vaccinated chick at 1 or 7 days-old for HI titer against AI virus in most ages. Moreover, fluctuated changes within the normal levels were noted at 14.28 and 42 days-old in plasma protein albumin globulin GOT. creatinine and urea in response to A1 vaccines at 1 or 7 days-old. It could be concluded that, both H5N2 and AI +ND vaccines were more preferable for Hubbard broiler flocks than H5N1 or the Egyptian A1 vaccines.
Keywords: Broiler, Avian Influenza Vaccines (H5NI, H5N2, Combinant Vaccine with Newcastle Disease), Productivity, Immune Response.
Publication year 2011
Pages 825-743
Availability location معهد بحوث الانتاج الحيوانى- شارع نادى الصيد- الدقى - الجيزة
Availability number
Organization Name
City الاسكندرية
serial title Egyptian Poultry Science
ISSN 1110-5623
Author(s) from ARC
External authors (outside ARC)
    حسام محمد صفاء جامعة القاهرة
    داليا ابو السعود عبد الله السيد جامعة القاهرة
    علاء الدين محمد عبدة جامعة القاهرة
    سوزان احمد رياض جامعة القاهرة
Agris Categories Animal feeding
AGROVOC
TERMS		 Broiler chickens. Immune response. Productivity. Vaccination.
Proposed Agrovoc Avian Influenza Vaccines;H5N1;H5N2;blood biochemical;
Publication Type Journal
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